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Synthesis and Characterization of Some Biologically Active Copper Complexes for Microbial Applications

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dc.contributor.advisor Aziz, Prof. Dr. Md. Abdul
dc.contributor.author Khan, Mohammed All Azom
dc.date.accessioned 2018-08-14T12:10:54Z
dc.date.available 2018-08-14T12:10:54Z
dc.date.copyright 2015
dc.date.issued 2015-06
dc.identifier.other ID 0000000
dc.identifier.uri http://hdl.handle.net/20.500.12228/397
dc.description This thesis is submitted to the Department of Chemistry, Khulna University of Engineering & Technology in partial fulfillment of the requirements for the degree of Master of Philosophy in Chemistry, June 2015. en_US
dc.description Cataloged from PDF Version of Thesis.
dc.description Includes bibliographical references (pages 50-57).
dc.description.abstract In this study, in order to verify our hypothesis amino acid base copper complexes have been prepared for biological application. Reaction of tcydan and Cu(C104)2 6H20 with nucleobases (adenine, hypoxanthine and theophylline) gave three tcydan—metal—amino-acid base complexes, Cu(tcydan)(ade)] .C104.2H20 (1), [{ Cu(tcydan) }2(hypoxanth).(CIO4)3 (2) and H20/CH3 [Cu(tcydan)(theophy)]3.(C104)3.2H20 (3). The complexes were prepared in H CN media at room temperature under pH 8-9. The crystal structures were determined by X-ray diffraction. In the structure of complex 1, the square-pyramidal Cu 2+ ion binds to an adenine ligand through the deprotonated N(9) and to four nitrogens of a tcydan ligand, and an interligand hydrogen bond is formed between the secondary amino nitrogen of tcydan and the ring nitrogen N(3) of the base. In complex 2, two square-pyramidal Cu2 ions bind to a xanthine ligand, one through N(7) with the formation of a hydrogen bond between the exocyclic oxygen 0(6) of the base and the secondary amino nitrogen of a tcydan ligand, and the other through the deprotonated N(9) with the formation of a hydrogen bond between N(3) of the base and the amino nitrogen of tcydan. In the structure of complex 3, the square-pyramidal Cu 2+ ion binds to a theophyllinato ligand through N(7) and four nitrogens of a tcydan ligand with the formation of a hydrogen bond between 0(6) of the base and amino group of tcydan, as observed in 2 and 3. In summary, the adenine complex 1 involves the metal-N(9) bonding with the formation of an N(3) hydrogen bond. On the other hand, the absence of the possible metal bonding to N(7) or N(I) of adenine might be due to a steric repulsion, intramolecular interligand N(tcydan)-H ...between amino groups of tcydan and the N(6) amino group when the metal ion binds to N(7)or N(l) of the base. Synthesized Cu-complexes are quite capable of removing Fecal coliform (FC) from water. en_US
dc.description.statementofresponsibility Mohammed All Azom Khan
dc.format.extent 50 pages
dc.language.iso en_US en_US
dc.publisher Khulna University of Engineering & Technology (KUET), Khulna, Bangladesh. en_US
dc.rights Khulna University of Engineering & Technology (KUET) thesis/dissertation/internship reports are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission
dc.subject Microbial en_US
dc.subject Biological products en_US
dc.title Synthesis and Characterization of Some Biologically Active Copper Complexes for Microbial Applications en_US
dc.type Thesis en_US
dc.description.degree Master of Philosophy in Chemistry
dc.contributor.department Department of Chemistry


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